A 100 mm QuikScale column was hydrostatically tested to 7 bar at the boundaries of the recommended operational temperatures. The QuikScale column has been engineered to minimize the effects of changing environmental conditions. Moreover, the mechanical strengths of materials change as a function of temperature, thereby imposing additional design considerations in order to maintain safe and predictable column operation. Under changing environmental conditions, dissimilar column materials expand and contract, often at divergent rates, potentially leading to seal and/or material failure. Excellent Performance over a Wide Range of Temperatures QuikScale columns are designed for use over a broad range of environmental conditions from 2 ☌ to 35 ☌. The consistent performance of the QuikScale column simplifies the validation efforts necessary to qualify the separation process as well as reducing manufacturing operating costs and processing time. The QuikScale column’s patent-pending liquid seals ensure operational integrity for reliable process handling. Flow tube kits are offered for QuikScale columns that are geared specifically for high throughput processing. The QuikScale columns contain stainless steel Porostar® bed supports and can operate with both soft gels and fast high-performance media for MAb purification. This technical brief will illustrate that the QuikScale column performs well over a wide range of temperatures and flow ranges. greater product purity at The design of the QuikScale column is uniquely robust, enabling the column to be used over a broad range of conditions in a variety of processing environments. ![]() Consistent Packing Performance for Diverse Media Types with QuikScale Biochromatography Columns TM The scalable family of QuikScale columns delivers faster linear velocities.
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